| Symex GmbH Co. KG | 🍎 | 1 | — | Productivity |
| Symmetry Club LLC | 🍎 | 1 | 4.8★ | Health & Fitness |
| Symphonic Hub Sociedad Limitada | 🍎 | 1 | 4.6★ | Music |
| Symphonio Borrys Hasian | 🍎 | 1 | — | Productivity |
| Sympla | 🍎 | 1 | 4.9★ | Entertainment |
| Symptom Recall LLC | 🍎 | 1 | 5.0★ | Health & Fitness |
| SynappseHealth Sp. z o.o. | 🍎 | 1 | 4.0★ | Medical |
| Synapsoft Corp. | 🍎 | 1 | 1.0★ | Productivity |
| Synaptic Edge LLC | 🍎 | 1 | 3.4★ | Utilities |
| Synaptic Labs | 🍎 | 1 | 4.7★ | Education |
| Synapticats, Inc. | 🍎 | 1 | 4.8★ | Health & Fitness |
| Synaptikon GmbH | 🍎 | 1 | 4.7★ | Education |
| Synapxe Pte Ltd | 🍎 | 1 | 4.5★ | Health & Fitness |
| Sync.ME LTD | 🍎 | 1 | 4.4★ | Social Networking |
| SyncPower Corporation | 🍎 | 1 | 2.9★ | Music |
| Syncbak, Inc. | 🍎 | 1 | 3.3★ | News |
| Syncfusion Inc. | 🍎 | 1 | 5.0★ | Business |
| Synclio | 🍎 | 1 | 4.5★ | Business |
| Synclusive Games | 🍎 | 1 | 4.4★ | Productivity |
| Syncly Applications | 🍎 | 1 | — | Productivity |
| Syncromatics | 🍎 | 1 | 3.0★ | Travel |
| Syncsing - Newzik | 🍎 | 1 | 4.7★ | Music |
| Synctuition OÜ | 🍎 | 1 | 4.6★ | Health & Fitness |
| Synectic Software Solutions, Inc. | 🍎 | 1 | 3.1★ | Food & Drink |
| SynergEV | 🍎 | 1 | 4.5★ | Navigation |
| Synergenics, LLC | 🍎 | 1 | 3.8★ | Lifestyle |
| Synergy Alliance Solutions Sdn. Bhd. | 🍎 | 1 | — | Business |
| Synergy CHC Corp | 🍎 | 1 | 4.6★ | Health & Fitness |
| Synergy MA | 🍎 | 1 | 5.0★ | Health & Fitness |
| Synergy Sports Technology, LLC | 🍎 | 1 | 3.8★ | Sports |
| SynergyBank | 🍎 | 1 | 2.7★ | Finance |
| Synerion Systems LTD. | 🍎 | 1 | — | Utilities |
| Synnax Studio LTD | 🍎 | 1 | 3.5★ | Utilities |
| Synovia Solutions LLC | 🍎 | 1 | 4.6★ | Education |
| Synovus Bank | 🍎 | 1 | 4.8★ | Finance |
| Synsidium Ltd | 🍎 | 1 | 4.6★ | Games |
| Syntaxity Inc. | 🍎 | 1 | 4.7★ | Games |
| Synthe FX, LLC | 🍎 | 1 | 4.6★ | Productivity |
| Synthesia LLC | 🍎 | 1 | 3.9★ | Music |
| Synthesis | 🍎 | 1 | 4.7★ | Education |
| Synthesized Software, LLC | 🍎 | 1 | 5.0★ | Reference |
| Synthetic Bits, LLC | 🍎 | 1 | 4.3★ | MUSIC |
| Synthiam Inc. | 🍎 | 1 | 4.4★ | Education |
| Synthify Inc | 🍎 | 1 | 3.8★ | Entertainment |
| Synxgen Technologies Pvt Ltd | 🍎 | 1 | — | Lifestyle |
| Syracuse University | 🍎 | 1 | — | Entertainment |
| SysCall AB | 🍎 | 1 | 5.0★ | Travel |
| Sysco Corporation | 🍎 | 1 | 4.7★ | Business |
| SystAG Systemhaus GmbH | 🍎 | 1 | — | Productivity |
| System D Labs Corp | 🍎 | 1 | 4.7★ | Games |